We also characterised the consequence of reducing MIF expression in B16-F10 cells in vitro in response to hypoxia, where MIF was proposed to play a role.
We have characterised the consequences of changing the amount of MAP4K3, encoded by hppy, in the development of the wing disc, focussing on its relationships with the TORC1 signalling pathway.
Given the widespread acceptance of HIF-1 α as a positive regulator of cellular proliferation (Dang et al, 2006), we characterised the consequences of HIF-1 α inhibition on gastric cancer growth.
In order to functionally characterise the consequence of the R234Q mutation identified, we performed two different assays concerning two processes, in which PTEN has been shown to play a key role, namely cell proliferation and apoptosis.
Therefore, we have compared irradiated human myeloid DC with untreated controls to characterise the consequences of irradiation on ex vivo DC applications or potential in vivo treatments.
In 2010, Monse et al. [ 21] introduced a new clinical index characterising the consequences of untreated dental caries in primary and permanent teeth: the pufa/PUFA index.
We will therefore investigate how Paget's disease has affected the proband, using the three health components of the International Classification of Functioning [ 34] to characterise the consequences of the disease, i.e. we will assess impairment of body functioning and structure, activity limitations and participation restrictions.
This type of analysis is typical of catastrophic top events, characterised by unacceptable consequences.
By using methods such as sedimentological evidence, historical sources, planimetric resurvey, repeated longitudinal and cross-profiling and hydraulic data, the geomorphological and hydraulic responses to channel changes are characterised and their consequences assessed.
However, FOXO3 expression in vivo is less well characterised and as a consequence, the clinical significance of FOXO proteins during CRC progression remains unclear.
