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They are unlikely to be the well characterised class 1, 2 and 5 Outer Membrane Proteins (OMPs) since these antigens do not induce a cross-reactive bactericidal immune responses in immunized volunteers [10].
Rearrangements of the cancer genome, including amplifications/deletions and chromosomal translocations, represent a biologically and clinically important, but poorly characterised, class of somatic variation in cancer.
For each of the species listed above, in addition to the CD94L sequence, we picked one representative of each of the characterised class Ia loci.
The best characterised class Ib molecules present the leader peptides of class Ia molecules to natural killer (NK) cells, that recognise them with their CD94-NKG2A and CD94-NKG2B inhibitory or CD94-NKG2C activating receptors.
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The genes that characterise Class A and Class B phenotypes and their expression by MSCs co-cultured with activated TIL are summarised in Supplementary Tables 3 and 4. A more focused analysis showed that in some melanoma samples both pro-inflammatory molecules and IDO are expressed and this concordant expression of divergent function may influence the overall behaviour of such tumours.
India is commonly associated with caste; while the Philippines is usually characterised by class or status distinction.
The research area was characterised as class I to IV on the CLSL and divided into 4 zones: negligible, low, moderate, and medium zones (Fig. 8).
In this study we characterised MHC class I in the common frog and developed primers to amplify exons 2 and 3 which form the antigen binding region (á1 & á2 domains).
The first study concluded that sickness absence during pregnancy in Sweden in the late 1980s was characterised by class differentials, but only marginal age differentials.
The two joined datasets are characterised by class imbalance, features imbalance, and imbalance of the number of observations between the modes.
Detailed analysis of cosmid clones containing the complement C4, C2, and CFB genes plus the CYP21 loci revealed a localised inversion of this sub-region such that the order of these genes in sheep is C2..CFB..RDBP..SK12VL..CYP21..C4..C4..CYP21..class II while in the well characterised human class III the order is C2..CFB..RDBP..SK12VL..C4A..CYP21A..C4B..CYP21B pseudo)..class II.
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