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Of the proteins that A-type lamins interact with, the best characterised are the so-called LEM domain proteins [12], including the integral membrane proteins emerin [13], [14] and MAN1 [15], as well as the nucleoskeleton protein LAP2α [16].
Many families of pattern recognition receptors have been identified although the best characterised are the Toll-like and interleukin-1 receptors (TIRs).
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However, one such system that has recently been experimentally characterised is the redCDEF system of M. xanthus [ 14].
One of the first of these proteins to be characterised was the yeast Snf2 protein (Laurent et al, 1991; Hirschhorn et al, 1992).
Ten different systems, which have been crystallographically characterised, are presented to illustrate the approach.
The first such transporter characterised was the P2 transporter.
The biological effects of IFN- γ are elicited through activation of intracellular molecular signaling networks, of which the best characterised is the JAK (Janus kinase -STAT pathway.
The best characterised are Th1, Th2 and Th17 cells.
It therefore seems probable that the absence of Gp210 from Fungi, where constituent Nups have been extensively characterised [48], is the result of secondary loss.
But like a number of traditional centre-right Labour figures he reflected that, under Tony Blair, he would be characterised as being on the left.
Lysosomal targeting of endocytosed membrane proteins requires specific signals, of which the best characterised is ubiquitination.
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CEO of Professional Science Editing for Scientists @ prosciediting.com