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As she argues: "My disaffection for genes arises in part from the instabilities or illogic I perceive in the characterisation of genes as facts.
Characterisation of genes related to insulin signalling in cats will prove useful to better understand the pathogenesis of feline diabetes and possibly of human T2DM.
Further characterisation of genes related to glucose metabolism in cats will provide additional insights into insulin-signalling mechanisms in this species.
This work focussed on characterisation of genes encoding the chloroplast-localised FKBP16-1 from wheat and its progenitor species, and identification of its putative promoters, as well as investigations into the effects of light regulation and plant development on its expression.
However the most convincing evidence to date has been the characterisation of genes mutated in familial PD with putative functional roles within mitochondria.
The recent sequencing of several vertebrate and invertebrate chordate genomes has widened the gap between the identification and the functional characterisation of genes.
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Using both in vitro and in vivo model systems of white and brown fat cell differentiation, we report a detailed characterisation of gene expression linked to mitochondrial biogenesis and function.
Here we report a comprehensive characterisation of gene expression linked to mitochondrial DNA replication, transcription and function during white and brown fat cell differentiation in vitro as well as in white and brown fat, brown adipose tissue fractions and in selected adipose tissues during cold exposure.
Another characterisation of gene regulatory networks is structural robustness [ 75].
Functional Genomics, the systematic characterisation of gene function, involves the study of large sets of proteins.
Several resources support computational drug repositioning based on transcriptional data and the functional characterisation of gene sets and signatures.
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CEO of Professional Science Editing for Scientists @ prosciediting.com