Sentence examples for chaperones help from inspiring English sources

In the crowded cell, chaperones help prevent partly folded proteins from bumping into other proteins that may try to swap elements or otherwise interfere with proper folding.

Chaperones help other proteins fold into the right shapes and protect them from interactions that might cause trouble.

Proteins called chaperones help protect cells from heat and chemicals that cause proteins to lose their shape and clump together.

Molecular chaperones help hundreds of signaling molecules to keep their activation-competent state, and regulate various signaling processes ranging from signaling at the plasma membrane to transcription.

Molecular chaperones help to restore the native states of proteins after their destabilization by external stress.

Because chaperones help confer robustness, their activity is also a prominent cause of cryptic variation [ 3, 8, 23].

Many of these proteins function as molecular chaperones, helping unfolded and misfolded proteins assume the correct conformation.

Like the polyQ model systems where molecular chaperones helped protect against cytotoxicity, overexpression of the molecular chaperone Hsp70 reduced cytotoxicity in C. elegans.

They act as molecular chaperones, helping to maintain the metabolic and structural integrity of the cell, as a protective response to external stresses.

In the absence of chaperone help, these proteins could aggregate, a toxic situation for the cell.

But because mutations induce a wide range of free energy changes, some mutations will terminally destabilize a protein (so that it must be disposed of), some will marginally destabilize it (so that it needs chaperone help to avoid aggregation or degradation during folding, but no more), and some will leave its stability unchanged or even stabilize it (no worries!).