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For the estimation techniques, static and dynamic approaches can be distinguished, according to the underlying assumption of the channel dynamics.
Reitz, M. D. & Jerolmack, D. J. Experimental alluvial fan evolution: Channel dynamics, slope controls, and shoreline growth.
We consider Markovian channel dynamics, relaxing the common but unrealistic assumption of i.i.d.i.d
Alternans was originally attributed to instabilities in transmembrane ion channel dynamics (i.e., the voltage mechanism).
In models incorporating the mutant channel dynamics, bifurcations are monostable; neurons which enter depolarisation block return to oscillatory behaviour when stimulation falls even just below the bifurcation threshold.
Channel dynamics were quantified by mean-squared-displacement (MSD) (Supplementary Fig. 16) and root-mean-squared-deviation (RMSD) (Supplementary Fig. 17) calculations.
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In the neuron, computational models suggest that transiently polarized microdomain ethenes may regulate ion-channel dynamics and control impulse propagation.
Basal ganglia model : selection processes between channels, dynamics controlled by contraction analysis, rate-coding model of neurons based on locally projected dynamical systems (lPDS).
Indeed, they correspond to an average over microscopic phenomena such as ionic channels dynamics.
In particular, their time scale must be sufficiently large to ensure that the description of ionic channels dynamics (opening and closing) in terms of probabilities is valid so dt must be larger than the characteristic time of opening-closing of ionic channels τ P. Additionally, Hodgkin-Huxley's equations use a Markovian approach (master equation) for the dynamics of h m n gates.
In the simulation presented in Fig. 3 G, voltage gated channels dynamics were modeled as in [19].
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