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A producer for the Tennis Channel burst in at one point, hurried and harried, and said, "All right, how are we doing here?" A cameraman dabbed sweat from his forehead.
In particular, the impact of desensitization on current deactivation is largely determined by the rate of the agonist unbinding (koff) that, as suggested by channel burst analysis (see later), is slower in α3β2γ2 receptors.
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α1-Adrenoceptor activation can inhibit sodium channel bursting via protein kinase C in ΔKPQ-SCN5A mutant cardiomyocytes.
The sample was illuminated at 488 nm, and light was collected in the green fluorescence channel; bursts with intensity greater than 10 counts/bin were counted, and the burst rate was determined to be 40 ± 10 s–1 (mean ± SD, n = 3; the burst rate from buffer alone was 0.16 s–1).
In the second quarter of this year, the number of viewers watching CNN dropped 2% from the same period last year, while the figure leapt at Fox News by 62% and at MSNBC by 25%.These upstart cable channels burst into 24-hour news at a time when CNN had begun to look staid.
To evaluate for possible aberrations in Ca2+-activated K+-channels, burst duration and repolarization were examined.
In the absence of T-type Ca2+ channels burst firing is not observed (Figure 3, red line).
We plotted burst onsets across all channels and found that burst onsets were visibly clustered across channels (Supplementary Fig. 3), enabling an automated selection of multi-channel bursts using a simple threshold.
To simulate losses, the memoryless Gilbert-Elliot (GE) model [17, 18] is used, as it is able to accurately approximate the behavior of a fading radio channel in burst applications.
Blockade of BK channels decreases burst duration in slices, suggesting that these channels slow down the depolarizing phase of the burst [21].
We identified periods in which a subset of channels exited burst suppression, defined as an interval of at least 30 s in which the channel did not undergo a suppression.
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