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Prior therapy with another calcium channel blocking agent, nifedipine, did not affect CyA pharmacokinetics.
Current focus is on the region- and transmitter-specific actions and Na+ channel blocking mechanisms of volatile anesthetics.
The anti-hypertension mechanism mainly relies on its L-type calcium channel blocking property.
Lercanidipine apart from calcium channel blocking activity possesses anti-oxidant, anti-inflammatory and anti-apoptotic properties.
We report two paediatric renal transplant patients in whom interaction with the calcium channel blocking agent verapamil resulted in reduced cyclosporin A (CyA) elimination.
Several hundred kayaks and other vessels also took to the water in the shipping channel, blocking access for any coal ships going in or out of Newcastle harbour.
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Worsening of congestive heart failure in amyloid heart disease treated by calcium channel-blocking agents.
Chhabra, S. et al. Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.
These models will help to design channel-blocking drugs with defined potency and selectivity of action.
Further extensive mutations of MeuTXKα3 at site 30 could help improve its K+ channel-blocking and antibacterial functions.
The addition of calcium channel-blocking agents to a standard hyperkalemic hypothermic cardioplegic solution has been examined both experimentally and clinically.
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