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The propagation boundary ∂R (σ = 1) can be obtained by changing the tissue excitability until open wave segments stop curling in to form reentrant SD waves with freely rotating open ends forming two centers (spiral SD) [58].
We considered that changing the tissue distribution of VDAs by targeting the drug to the tumour vasculature could be a strategy to improve the therapeutic effectiveness of these compounds.
By increasing or decreasing the number of injected leukemic cells, we can modulate mice survival without changing the tissue distribution of leukemic cells and their engraftment in NSG mice.
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However, the breast is a highly radiosensitive organ: the International Commission on Radiological Protection (ICRP) has varied its estimate of the contribution of breast radiation exposure to total body detriment over time, changing the tissue-weighting factor for this organ from 0.05 in 1991 [2] to 0.12 in 2007 [3].
In conclusion, a deficiency of eNOS-derived NO may change the fat distributions in the liver and viscera, thereby promoting the progression of disease in an HFD-induced, early-stage NASH mouse model by changing the hepatic tissue blood flow.
A multiscale model of bending stiffness is proposed to capture the impact of changing the constituent tissues and the cross-sectional geometry.
Thus, the higher ratio of n-3/n-6 PUFA entering the cellular pool from dietary sources could be involved in BC carcinogenesis by changing the balance of tissue eicosanoids.
Furthermore, Wagner et al demonstrated that human spinal disc tissue treated with methylglyoxal contained significantly increased amounts of AG Es changing the biomechanical properties of the tissue.
Additional sensitivity analyses were conducted to show that both changing the fu in lung tissue as well as the addition of an uptake transporter activity from the blood to lung tissue resulted in changes in the plasma/blood to lung tissue ratio.
In fact, tissue blood flow must be adjusted to ensure sufficient oxygen extraction as capillary dysfunction becomes more severe, thereby changing the normal relationship between tissue oxygenation and blood flow.
Moreover, postmortem artifacts like stromal edema and corneal autolysis can potentially change the tissue ultrastructure thereby changing the effective corneal birefringence properties, which may further increase the disparity between the predicted and measured data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com