Sentence examples for changing the localization of from inspiring English sources

Changing the localization of glycosylation enzyme GnT III has been attempted in mammalian cells [54], which resulted in an increase in the proportion of GlcNAc bisected, non-fucosylated, hybrid-type glycans.

K63-linked chains have important functions in activating kinases in the NF-κB pathway, orchestrating events during DNA repair or changing the localization of membrane proteins.

Miyoshi and Kondo (2013) applied a multi-scale localization approach by changing the localization scale, depending on the scales of error correlations, and reported promising results.

The effects of phosphorylation can be mediated either by remodeling ribonucleoprotein complexes (mRNPs) via altering protein protein or protein RNA interactions or by changing the subcellular localization of the splicing factor.

We have identified a novel ubiquitin (Ub) Lys linkage on CIITA IF3 and further show that Lys ubiquitination is an important modification for changing the subcellular localization and thus activity of the MHC II master regulator.

Thoulouze et al. also reported that in addition to changing the steady state localization of Lck, Nef impairs the recruitment of Lck to the IS following TCR engagement [15].

Therefore, changing expression levels, isoform expression, and alternative polyadenylation cannot explain the changing localization of the majority of mRNAs.

Conversely, replacement of the NFC domain in EerI with another aldehyde can abolish its cytotoxic activity without changing the ER localization.

Using this 'localization-dendrogram', we revealed that the changing localization of single mRNAs is a global feature of localized mRNAs and occurred at all stages of oogenesis.

This resulted in mainly cytoplasmic localization of the protein without changing the amount of protein, similar to what we observed previously when C33 was deleted entirely.

Subsequently, calcineurin is activated and dephosphorylates NFATc2 at 13 conserved phospho-serine-residues, changing the conformation of NFATc2 and thereby unmasking an NFAT nuclear localization site (Fig. 7, left).