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Satellite/centr may change expression of nearby genes via changing the binding of the transcription factors to chromatin [ 53].
Authors concluded that the delamination length can be reduced by changing the binding sequence to one with shorter binder spacing/ smaller unit cell size.
The release kinetics of growth factors can be molecularly modulated by either changing the binding affinity of the aptamer or by using a triggering effector.
Variations of the aptamer selection strategies can be used to isolate catalytic nucleic acid sequences by changing the binding selection step of the aptamer selection process to an activity selection step (Fig. 15).
Therefore, we proposed that by changing the binding affinity of the fibroblast to collagen, integrins are causing the induction of intracellular ROS, which leads to oxidant stress and caspase-3 activation.
Recently, we proposed that the ATP-binding event in NBD94 triggers a conformation rearrangement within the protein, going along with alterations in Py235 and thereby changing the binding strength of this reticulocyte binding-like protein to the red blood cell, as reflected by erythrocyte binding assays performed with Py235 of P. yoelii [27].
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Indeed, our hypothesis can be validated experimentally; by changing the Gcn4p binding site for gene ILV5 to have a lower binding affinity, it predicts that the regulation of the amino acid biosynthesis pathway will be disrupted more easily.
3DP is very versatile as without changing the primary binding material an array of material properties can be achieved by using different powdered materials and adding infiltrants.
In agreement with the model predictions, experiments reveal that the isocost line rotates when changing the ribosome binding site strength of the inducible gene and shifts when modifying the plasmid copy number.
The importance of this splicing event for eye formation is underscored by its conservation among several Drosophila species and its involvement in changing the DNA binding properties of a hallmark feature of Pax gene family, the PD domain.
We therefore concentrated on changing the substrate binding orientation by altering residues that directly or indirectly contacted the alkene.
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