Sentence examples for changing specificity from inspiring English sources

These lead to direct sequence changes of sensors and regulators, eg, changing specificity of stimulus or allowing the regulation of new genes.

While AN19NGG sites might be predicted to occur roughly at the same frequently as GN19NGG sites, we found that they are actually 15% more common (Fig. 2; Supplementary Fig. 3); thus changing specificity from GN19NGG to RN19NGG more than doubles the number of available sites.

A final question is whether the changing specificity of c-Myb is linked to its potential oncogenic activity.

Chemo-vaccination-induced T cell responses were robust (up to 3,940 SFU/106 PBMCs), predominantly central memory cells, short-lived (≤22 weeks), and appeared intermittently and with changing specificities.

The effector specificity could be rationally changed by changing the specificity of the conjoined aptamer: when a mutation was introduced into the anti-theophylline aptamer that led to discrimination against theophylline and in favor of 3-methylxanthine (that also differed from theophylline by a single methyl group), the aptamer became solely responsive to 3-methylxanthine in vivo.

It could also be argued that since the MDH/LDH system simply involves changing substrate specificity, that the change is not particularly 'neo' but rather a tuning of an existing function.

However, patterns of changing CTL specificity and viral mutation in natural infection, in addition to data from macaque and in vitro studies, suggest that a more focused approach might optimize the activity of vaccine-generated CTLs to prevent or attenuate infection.

It provides a new direction for future research into changing the specificity of REases.

The presence of this helical-segment in expanded variants of PABPN1 could modulate their interactions properties by changing partner specificity and/or affinity.

Directed evolution techniques can now be utilized to generate [NiFe]-hydrogenases with tailored catalytic activity, oxygen sensitivity, and potentially even changing coenzyme specificity.

During this recombination process one of several sets of downstream CH exons replaces the Cµ exons and the intervening sequence is deleted from the chromosome, which results in expression of a new C region without changing the specificity of the IgH variable region [5].