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If somatic mutations were changing recognition of mitochondrial peptides from self to non-self, then any inherited changes would be irrelevant.
Furthermore, this method might be extended to sensitive detection of other proteins by changing recognition elements of proximity probes.
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Most approaches to melanoma diagnosis have included emphases on recognition of changing lesions, recognition of outlier ("ugly duckling") lesions, and specific melanoma features, with the most utilized criteria being the ABCDE descriptors.
The EU is changing beyond recognition this weekend.
THE bicycle-making business is changing beyond recognition.
It added: "Since the disaster, football has evolved immeasurably, with all stadia and associated safety procedures changing beyond recognition in the intervening years.
Its 50th anniversary, coming Sunday, made Mr. Joo reflect on a North Korea that, to him, has remained unchanged and on his own society, which seems to be changing beyond recognition.
But this idyllic spot may soon be a thing of the past, with the threat of Bali – population 3.5 million – changing beyond recognition, a prey to the accumulated effects of mass tourism, unbridled consumption of resources and environmental collapse.
Two small, weak telecoms-equipment firms became one big, weak one, beset by low-cost competition from new Chinese rivals and struggling in a business that internet technology was changing beyond recognition.
http://t.co/WlnSAXGqUe #Fallon And there were opinions on both both sides of the argument: @guardian They are! Immigrants are not the reason for peoples ills but the fact remains, communities are changing beyond recognition.
Ms. Rowling, the author of the Harry Potter novels, said in a statement, "I cannot, in good conscience, continue to be the public face of a charity that is changing beyond recognition from the one with which I have been so proud to be associated".
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