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Allied to the changing pattern of disease, reports of resistance to triclabendazole (TCBZ) have appeared in the literature, although they do not all represent genuine cases of resistance.
A changing pattern of disease epidemiology was signalled by reports from the United States in the late 1990's of MRSA infection in otherwise healthy children who lacked exposure to an institutional health care setting or other risk factors typically associated with MRSA colonization [2], [3].
This changing pattern of disease will therefore require health policy and interventions that differ from traditional vertical approaches and single disease management such as integrated management of chronic disease patients considered to be stable [ 23].
However, in addition to the changing pattern of disease, reports of resistance to TCBZ have appeared in the literature [ 62– 64], although they may not all represent genuine cases of resistance.
When the context of SMRU's broadening research agenda and history is taken into account, the disease target can be said to reflect the shift in SMRU's research agenda in accordance with the changing pattern of disease on the border.
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The complexity within the system is an interaction of political, economic, social, demographical changes and the changing patterns of disease [ 2].
The Lancet commission has further identified the following six ways in which climate change can affect human health: Changing patterns of disease and morbidity, food, water and sanitation, shelter and human settlements, extreme events and migration (2).
Demographic change, acting through these developmental processes, may also play a role in the changing patterns of disease.
The demand for care at home is set to grow rapidly – changing patterns of disease and demography will see more us with long-term conditions and frailty in older age.
But the changing patterns of disease pose another dilemma - a growing burden of ill health.
It is a widely held assumption that the major changes in the abundance of surface water between the flood and dry seasons in the Mekong Delta are likely to be reflected in the changing patterns of disease risk, especially for poorer households that tend to rely heavily on river water for domestic water use.
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CEO of Professional Science Editing for Scientists @ prosciediting.com