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The precipitated DNA was amplified by semiquantitative PCR and ARS-specific enrichment was normalized to the loading control and the input, which accounts for changing copy number between different chromosomal locations during S-phase (Fig. 5D and 5E).
Gene conversion is used to explain concerted evolution between duplicated genes (two copies) without changing copy number [ 30, 31].
The results also implied that the actin gene family might obtain new function or alter original function by changing copy number in the genome during the evolutionary process.
It is likely that the difference in YFP fluorescence over the 14-day period was due to the changing copy number of pCA2.4 relative to the chromosome number during the cell cycle [ 16].
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Because the sensitivity value changes depending on copy number variation, we obtained a maximum sensitivity value by changing the copy number variation from 0.001 to 1000.
In this case, the dynamics of the altered regulatory genes with increased copy numbers should be confirmed in advance, because changing the copy numbers and expression of regulatory genes would alter the dynamics between regulatory genes.
Applying this unbalanced increase in mtDNA degradation without a matching change in replication has a strong effect on mtDNA dynamics as it corresponds to a universal change in the 'control' applied to the system, analogous, for example, to changing target copy numbers in manifestations of relaxed replication (Chinnery and Samuels, 1999).
He never bit my head off for changing his copy.
I complained about the Foreign Desk's changing my copy in a letter to foreign editor Nate Polowetzky.
It's going to take agents calling and saying NO, actors passing on projects, directors changing the copy and ultimately not expecting anyone else to do the work for you.
This could be due to either low gene duplication rate compared to divergence time, or negative selection that prevents certain gene families from changing their copy numbers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com