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Changing cell migration speeds above zero, while keeping cluster migration speed fixed at the normal value, failed to alter ALC diameters at any of the initial densities tested.
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Changing cell and/or cluster migration speeds using cells that relied on the random migration mode only (Fig. S2) also failed to significantly alter final ALC diameters: changes, relative to those in Fig. 11, were muted.
Two types of changing cells were identified.
If MHCK A is inactivated in the pseudopod by an unknown signal promoting pseudopod retraction, myosin II will be poised to assemble in the pseudopod, thereby changing the direction of cell migration.
MiR-200a played important roles in the MET process of CSCs by changing EMT markers expressions and cell migration and invasion.
In vivo studies have also demonstrated that APC loss or mutation impedes enterocyte migration along the crypt-villus axis [ 34, 35] and forced overexpression of APC results in disordered, non-adhesive intestinal cell migration, presumably by changing the relative activity of cadherin-catenin complexes [ 36].
Eliciting a cellular response to a changing chemical microenvironment is central to many biological processes including gene expression, cell migration, differentiation, apoptosis, and intercellular signaling.
These experiments present the first demonstration of cellular response to changing haptotactic gradient slope using an in vitro system for the quantitative study of cell migration.
We demonstrate that changing the arginine of this motif severely impacts the ability of this GPCR to function in primordial germ cell migration during Drosophila embryogenesis.
Changing the local rheology or the nanotextured surface of substrates has proved an efficient approach to improve cell lineage differentiation, to control cell migration properties and to understand environmental sensing processes.
Cell migration.
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