The c-2J mutation spontaneously arose within a C57BL/6J colony, resulting in a R77L amino acid substitution and also changing alternative splicing of the tyrosinase pre-mRNA [ 39, 40].
Additional proteins targeted by miR172 that are likely candidate proteins affecting fiber development include phosphoenolpyruvate carboxylase [ 31], the glutamate receptor involved in dendritic cell growth [ 32], and YT521-B-like family proteins changing alternative splice site usage in concentration dependent manner [ 33].
I used to be a stickler for this point of usage, always changing "alternate route" to "alternative route," although the shorter version is more often seen on road signs ("USE ALTERNATE ROUTE").
Spending hundreds of millions of dollars to increase any city's dependence on the automobile when we should be thinking about less climate-changing alternatives would be retrograde, to say the least.
Nor has either candidate budgeted for changing the alternative minimum tax, which was originally created to prevent the wealthy from taking too much advantage of sophisticated tax breaks.
Policymakers from across the world met recently in Vienna to agree to phase out HFCs but some countries are nervous about the extra cost of changing to alternative refrigerants.
White House aides have said the president is open to other methods of equalizing the burden, including changing the alternative minimum tax — which now affects many middle-class taxpayers — to apply specifically to millionaire-level income, and at a much higher rate.
Little progress was seen during this meeting, as the County Governor's representatives focused on the potential of changing to alternative income activities for the farmers that would not be sensitive to carnivores.
It also encodes the potential to adapt to changing or alternative environments [ 43, 44].
From the analysis of the optimal-observer model, two important properties of behavior in the RDM task emerge: First, the change over time in posterior probability is affected by the location of the choice alternatives, and therefore indirectly by the number of alternatives, because changing the number of alternatives affects the location of the alternatives.
Function-changing alternative splicing has also been observed in rice.
