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Chair-chair interconversion is a complicated process brought about by successive conformational changes within the molecule.
One might speculate about substantial changes within the molecule generated by different interactions between the backbone and the side-group resulting in structures that discriminate between the two channel types.
This could happen through triggering conformational changes within the molecule, or simply by positioning these domains in spatial proximity to their interaction partners at the nuclear membrane, creating a sort of plectin-dependent microenvironment.
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11 It may be concluded that the observed shift with increasing pressure is consistent with conformational changes within the molecules rather than changes in interauric distances.
This could be reversed by further changes within the eRF3 molecule.
There was also the attempt to look at the correlation of the presence of certain TRAP sequences to survival in infected birds and this was discussed, in part, with particular changes within the TRAP molecule.
We can understand the dependence of the preexponential factor on alkane chain length in terms of conformational changes within the alkane molecules.
"Small changes in the molecule can make it either not effective or tremendously potent".
The 419 439 and 426 441 sequences are in the β20 β21 hairpin domain, which changes conformation within the gp120 molecule upon CD4 binding, and is part of the bridging sheet involved in interacting with the chemokine receptor during HIV entry [19].
The Maspin G-helix is capable of an "open and closed" conformational change inducing redistribution of charged residues within the molecule.
Fluorescence transduction signal mechanism, which is influenced by changes within the chemical environment of a fluorophore molecule, has enabled MB to function as ultrasensitive probes for real-time monitoring whilst generating high background signal-to-noise ratio.
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