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This study was designed to detect the placental changes in pregnancy associated with DM comparing these changes with normal placenta.
> -wrap-foot> ECG showed sinus tachycardia and non-specific ST-T wave changes with normal corrected QT interval.
Figure 4 d) shows cardiac tissues of barley bran-fed group showing disappearance of pathological changes with normal cardiac tissue.
As an alternative, an appropriate measurement of intact architecture should provide a neuroanatomical index that precedes pathology, changes with normal ageing, and correlates with cognitive ability [ 8].
Specifically within the SN it is the dopaminergic neurons of the pars compacta that are lost and interestingly, this brain region also shows more pathological changes with normal ageing than any other region (Fig. 1).
DOI: http://dx.doi.org/10.7554/eLife.00324.026 10.7554/eLiFigure24 figuregure 4—figure supplement 7. Early vascular changes with normal retinal structures occur in homozygous conditional Flt-1 knockout mice ( Vmd 2 -cre + flt-1 lox/lox ).
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PAA-BA also exhibited better tissue compatibility, reflected by no or less inflammatory response in the site of muscle injection at the same (0.03% w/v) or higher concentration (0.1% w/v) and no hepatic tissue morphological change with normal hepatocytes.
A study of the dorsolateral PFC found that the microstructure changed with normal ageing and that minicolumn thinning and accumulating plaque load mirrored the decline in IQ [ 8].
Importantly, circadian rhythms change with normal aging in animals and humans, including a shift in the phase and decrease in amplitude [ 15- 18].
Therefore, while increased LTCC function is a significant source of the age-related cognitive deficits, other sources of Ca2+ that are changed with normal aging should also be systematically characterized.
The human voice undergoes changes associated with normal physiological aging after the age of approximately 65 years.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com