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Therefore, a relatively small population of individuals can provide an allelic series that includes a variety of missense changes with differing effects on protein function, and nonsense or splice site changes that cause truncation of the gene product.
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One intervention home and the matched control home specialised in dementia care as care homes in Norfolk were on the cusp of becoming mixed homes with some residents with dementia, enabling the appropriateness of changes across populations with differing levels of cognition to be addressed.
Our study adds to a collection of phylogeographical studies on carnivores, which when looked at together indicate that there may be a difference in response to historical climatic change between species with differing traits such as dispersal rates and adaptability.
However, sub-group analysis showed similar figures for change in management with differing time intervals between FDG PET-CT and CECT examinations.
In the analysis of electronic patient records, different medical codes for a single condition may have varying clinical and prognostic significance; utilisation of different medical codes may change over time; researchers with differing clinical or epidemiological experience may have differing interpretations of the relevance of particular codes.
By detecting radical amino acid changes (i.e., changes between two amino acids with differing chemical and physical properties) and their functional role in predicted 3D structures, the above authors proposed a correlation between the physiological consequences of those changes and some life cycle traits in the species examined.
Population average telomere length demonstrably can change over evolutionarily short timescales, with differing mean LTL reported between ethnic groups (Aviv et al., 2009) and countries (Eisenberg et al., 2011).
Climate change acts at many levels and with differing relative influence in its impacts on health outcomes.
The e-mail leak is also sparking a broader debate about the Intergovernmental Panel on Climate Change, with sharply differing views about the body's effectiveness.
The detection of a significant cohort of developmentally regulated trypanosome mRNAs by microarray, and their validation by qRT-PCR, provided confidence that our procedure could be exploited for investigation of transcriptome changes associated with differing conditions.
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