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Only mild systemic physiological changes which may impact image quality can be expected if scan acquisition is performed within 4 minutes after nitroglycerin administration.
In addition, A βo binds to membranes directly which appear to involve GM1 ganglioside and as such are thought to induce structural and functional changes which may impact Ca2+ signalling and synaptic plasticity [ 20, 21].
Use of PAT in Supporting Post-approval Changes to IR and MR Products: The principles for the SUPAC QbD approach are based on product-specific risk assessment of changes which may impact approved design spaces within the framework of the approved control strategy to ensure consistent product quality and performance.
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In addition to alteration of nucleosome positioning as a cell transits through mitotic division [ 8], there are a number of posttranslational histone modifications that are either maintained or changed, and which may impact gene expression after mitotic exit [ 9 12].
Sensitivity analyses will explore the impact of both the magnitude of change considered important and any congruent negative changes which may affect conclusions of efficacy.
Researchers also lacked data on how the proportion of foreign medical graduates practicing in the U.S. has changed over time, which may impact their contribution to research.
Pregnancy is a complex event characterized by changes in numerous factors which may impact the CNS.
These gene expression differences suggest notable sex-related changes in protein expression which may impact their use and utility.
In support of this data, previous in vitro studies have suggested that *105Val amino acid may confer protection against Hg-induced inhibition due to structural changes in cysteine residues which may impact the ability of Hg to bind and, consequently, inhibit the enzyme [ 38, 39].
The distance between vehicles will change with different Dstandstill setting, which may impact communication.
However, moonlighting could also change staff perceptions, decisions, and behaviours, which may impact on turnover at their primary jobs either positively (in the decision to stay because of alternative benefits provided by the secondary job) or negatively (in accelerating actual turnover) (47).
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