Although central venous oxygen saturation (ScvO2) is an alternative parameter, its changes are unable to detect regional hypoxia.
These instruments are preferably self-administered by workers with health impairments because objective measurements of productivity changes are unable to capture reduced productivity while still at work (i.e. presenteeism).
On the other hand, another study on RR MS, focused on the thalamic RSN, reported a decreased performance associated with increased FC, suggesting that neuroplastic changes are unable to fully compensate for cognitive dysfunction [ 51].
In general, such modification (when only atomic-deficient free-volume structure is changed) is unable to accommodate RE ions obeying electrically active state (RE3+), avoiding non-radiative decay [5, 14, 17, 18].
Interestingly, the D-helix mutant of MENT, which does bind DNA, but doesn't undergo conformational change, is unable to condense chromatin, suggesting that the conformational change induced in MENT may play a role in chromatin condensation carried out by this serpin.
Our results clearly indicate that the Arg229Gln amino acid change was unable to protect mtDNA integrity from oxidative damage(s).
Whether, the turnover rates of the specific proteins leading to the metabolic changes and decreased oxidative capacity were affected by hypoxia or not or the changes yet were unable to exert functional changes are unknown.
Therefore, despite rapid evolutionary changes, populations were unable to revert to their original fitness level unless these changes modified their fitness optimum.
They told me that he had made so many changes they were unable to keep the names straight.
Given the multiplicity of ultrastructural changes, we were unable to reliably identify the specific structures that are caused by Gln1.
