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"She was able to show that genetic changes were defining specific types of cancers, and it was these genetic abnormalities that were really the trigger to explaining why cancer behaved the way it behaved".
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Finally, "flip" exon changes were defined as any case where exons in the same event were positioned on opposite strands.
Intron gain/loss changes were defined as single exons that overlapped 2 or more exons in the other genome.
Exon gain/loss changes were defined as single exons that overlapped no exons in the other genome.
Weight and BMI changes were defined as main outcomes.
Gross chromosomal changes were defined as changes that involved an entire or almost entire chromosome.
Thirty protein changes were defined that were significantly associated with the extent of liver fibrosis.
Participants without these changes were defined as the healthy control group.
Cystic changes were defined as more than one hypoechogenic area > 1 mm.
Fold changes were defined as ratios of mean expression values for glioblastoma versus normal brain samples.
Three recent stressful life changes were defined: marital problems, recent unemployment and household financial problems.
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