Taken together with the earlier finding that the undifferentiated ME-iPSCs and TF-iPSCs showed similar gene expression, our data suggest that these changes are acquired during differentiation.
These cells have to be expanded in vitro before transplantation and several studies demonstrated that long-term culture evokes continuous changes in MSC: proliferation rate decays, the cell size increases, differentiation potential is affected, chromosomal instabilities may arise and molecular changes are acquired.
Extension change data were acquired at 66 kHz and boxcar averaged to 10 Hz (dark color).
However, as mentioned above, the avian-human reassortant influenza virus in the study of Imai et al. transmitted via the airborne route after passaging in ferrets, when a few additional genetic changes in HA were acquired.
The AC and DC components of reflectance (R) and differential changes in R (ΔR) were acquired by a computer, simultaneously.
The changes of copy numbers were acquired while UPDs were constitutional.
In particular, Mr. Grassley asked the agency to examine how many nursing homes had been bought by private investment groups and how conditions had changed after those homes were acquired, and to examine the number of health and safety deficiencies cited by regulators at those homes.
The whiz kids infuriated crusty airmen like Gen. Curtis LeMay (who told Los Alamos bomb designers back in the 1950's that he wanted one bomb big enough to destroy all of Russia), but they changed the way weapons were acquired by the Pentagon.
Lateral radiographs of the cervical, thoracic and lumbar spine were acquired and changes related to AS were assessed using the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS).
To characterize the time scale of the change in cell morphology, images were acquired at 5 minute intervals following centrosome irradiation in 26 cells (Figure 6B).
