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Thus, changes to the gut microbiome can precipitate disease.
The scientists observed that the changes to the gut microbiome brought about by obesity persisted for five times as long as the actual period spent dieting and predisposed the mice to rapidly regain weight.
Our study does not yet clarify whether the changes to the gut bacteria are a cause of poor ageing itself or are just a consequence of frailty – longitudinal studies that follow people over several years will be needed to sort this out.
Scientists have linked obesity, for example, to changes to the gut's ecosystem.
Similar changes to the gut may also increase reproductive success in humans and other mammals.
However, physical exercise appeared to dampen changes to the gut microbiota.
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Changes to the microbiome regulate gut permeability and increase hepatic exposure to injurious substances that increase hepatic inflammation and fibrosis.
However, it is unknown to what extent these S. enterica adaptations will result in changes to the composition of gut microbiota.
However, the changes to the lining of the gut that they report are not unique indeed, according to a textbook written by one of Dr Wakefield's co-authors, these changes are often present in normal people.
Changes to the diversity of the gut microflora in and elderly individuals correlate strongly with effects on health status and may contribute towards their increased inflammatory status [ 9].
McConnell has been leading a group of 43 senators -- under Senate rules, a minority of 41 or more senators can block action -- who are demanding gutting changes to the Consumer Financial Protection Bureau's funding, authority, structure and independence as their price to confirm the CFPB's well-qualified director, Rich Cordray, to a full term.
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