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Although a few reports describe application of stereological methods to quantify neuropathological features in correlation with behavioral changes to study encephalitis [32], [33], [34], none have investigated the effect of an EE on viral encephalitis.
Changes to study conduct after trial initiation but before the close of enrollment can impact recruitment.
Any changes to study procedures or protocols that were needed were fully discussed and implemented at both sites.
To address these issues, we propose changes to study recruitment practices and attempt to guide investigators to consider potential pitfalls in the way they conduct recruitment and retention.
In the event of changes to study design requiring significant amendment to the content of the participant information sheet, participants will be required to provide renewed informed consent.
The analysis will be performed according to the intention-to-treat principle, by assigned study treatment and ignoring changes to study treatment during follow-up.
Similar(52)
Could the shift from studying how climate changes, to studying ways of mitigating and adapting to climate change, be a good thing?
The excitation phases are changed to study the radiation pattern of each patch array antenna with different orientations.
For example, in case one, RS initially aimed to study pre-hospital care but in response to the local partner's needs, changed to study the emergency department.
Then, the incentive region is changed to study the identification effect under different interactive impact conditions, where the contact condition of the ball screw is different.
The number of layers and layer compositions are changed to study the effect of layer thickness on the crystalline morphology of the HDPE layers under confinement.
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