Sentence examples for changes to pathways from inspiring English sources

Biological pathways such as those captured by KEGG (Kyoto Encyclopedia of Genes and Genomes) [ 5] are manually drawn pathway maps linking genes to pathways; KEGG pathways have limited computational value for analysis of systems biology data sets beyond directly mapping observed changes to pathways and assessing over-representation.

As an alternative approach, recombinant antibodies expressed in plants have been used to inactivate or sequestrate specific host proteins or compounds, resulting in significant changes to metabolic pathways.

These findings suggest that consuming broccoli interacts with GSTM1 genotype to result in complex changes to signalling pathways associated with inflammation and carcinogenesis in the prostate.

The second method combined protein-protein interaction (PPI) networks with gene expression changes to identify pathways altered following Flovent treatment.

We are aware that during this period some trusts have made changes to patient pathways and to the way data are acquired.

Although peripheral tissue injury is undoubtedly important for the initiation and maintenance of arthritic pain, more central factors, involving changes to pain pathways, become equally important with time.

However, numerous genes do not produce apparent phenotypes when knocked out, even though statistically significant quantitative changes to biological pathways are observed.

There are numerous genes for which loss-of-function mutations do not produce apparent phenotypes even though statistically significant quantitative changes to biological pathways are observed.

It describes the advantages of doing so for patients and for the service; and outlines changes to care pathways that introducing the technology would require.

Here, we analyse the transcriptome of cisplatin-treated cancer cells, and use AS changes to identify pathways that link cisplatin with the cellular response.

34 This will require the flexibility to allow changes to patient pathways, to support additional investments in training, equipment and infrastructure, and to improve access to rehabilitation services if necessary.