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We provide other recommendations about how WHO can improve the implementation of organizational changes to guideline development in other articles in this series [ 6, 46- 50].
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Limitations to TPA administration were late recognition of submassive PE and inadequate knowledge of changes to guidelines.
Introducing this service is only effective if doctors initially assessing these patients are aware of recent changes to guidelines for PE.
Changes to guidelines and practice started to occur in the early 2000s when statin use was recommended regardless of lipid levels [ 36], but it may have taken several years for this recommendation to gain widespread adoption by clinicians.
Furthermore, further research is suggested surrounding the economic and health impacts of changes to guidelines surrounding vaccination, antimicrobial acquisition and use, as well as increasing the frequency of contact between producers and practitioners.
Now, after a year of campaigning, Hart is forcing a change to guidelines on media coverage that will encourage a greater accuracy in reporting domestic homicides.
She had argued the change to guidelines could "change how we view death", and create "a new mean whereby euthanasia is an accepted form of behaviour" High Court judges Sir Brian Leveson, Mr Justice Wilkie and Mr Justice Cranston unanimously ruled the legal challenge lacked merit and refused to quash the amendment.
The women in this study were pregnant at the cusp of a change to guidelines from guidelines recommending low alcohol consumption to guidelines recommending abstinence.
In 2016 the NIH proposed limited changes to the guidelines (SciPol brief available here), but has not yet issued final, updated guidelines.
Ultimately, ensuring guideline adherence requires a gargantuan effort from those in leadership such that the culture of the organization changes to embrace guidelines as part of standard work.
Even minor changes to the guidelines would be significant.
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