Exact(1)
Although genetic deletion of adiponectin may provide important clues to the molecular mechanisms of adipokine-induced physiological changes, the relevance of this genetic model to human patients who do not carry genetic deletion of adiponectin is questionable.
Similar(59)
When unpublished material is found, it often does not change the relevance of a result [ 54- 56].
Together, the results change the relevance of marsupial syndactyly from being an enigmatic phylogenetic character within marsupials to a rare transformation of digit morphology whose molecular background has the potential to provide important insights into the patterns of digit evolution.
"What's changed is the relevance of local and organic produce.
Now, the world's largest network is making a couple of changes to improve the relevance of the items.
In other instances, knockout studies have changed views of the relevance of 5-HT homeostasis in brain development and plasticity as well as processes underlying emotional behavior.
Also, because even small changes in tissue microenvironment can induce major changes in monocyte/macrophage phenotypes, the relevance of results from the experimental manipulations performed in animal models to human disease may be limited.
Further research is required to establish what role epigenetic changes play in mediating observed changes in gene and protein expression, and the relevance of these changes to health.
The fact that environmental B. anthracis isolates have such varied inducible prophages that enable the phenotypic changes described here, supports the relevance of our assertions.
(3) Although associated with mood changes in female subjects, the relevance of altered estradiol function to this male group is underscored by local aromatase mediated conversion of testosterone to estradiol, including in the amygdala, where it modulates anxiety and depressive-like behaviors [32].
Due to the fact that targeted therapies induce metabolic changes in glucose metabolism, the relevance of [F]FDG-PET/CT was also discussed.
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