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We identified CpG methylation changes that progressed with disease severity and distinguished stage III ovarian cancer from normal or LMP ovarian tissue.
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These reactions include the serotonin syndrome, which includes the following signs: hyperthermia, rigidity, myoclonus, autonomic instability, and mental status changes that may progress to delirium or coma.
Clinically, essential tremor is now considered a neuropsychiatric disease that can include unsteadiness, abnormal eye movements, problems with coordination and cognitive changes that sometimes progress to dementia.
Cervical intraepithelial neoplasia is a possible result of the biopsy, and represents dysplastic changes that may eventually progress to invasive cancer.
Early detection of prostate cancer is hindered by an inability to distinguish between histological presence of cancerous changes that may never progress to potentially fatal metastatic disease (Culig et al, 2002).
However, when HPVs succeed in evading innate immune recognition and elimination, continued persistence of the viruses can cause dysplasia, the precancerous but reversible changes that may slowly progress to cancer.
Perhaps, I reflected, despite all the changes that progress brings, good and bad, it is one step forward when real tribal violence becomes just a film about it.
All three of these fibrotic diseases undergo metaplastic changes that progress to tissue calcification, suggesting an association between chymase-expressing mast cells and tissue metaplasia.
Whether components of tobacco smoke affect the progression of lung cancer is currently not known, although a recent review suggests that tobacco derived carcinogens such as aromatic hydrocarbon compounds may induce cellular changes that progress the disease.
5, 6 Consistent with the prominent role of NMDARs in glutamatergic transmission as well as activity-dependent plasticity, symptoms of anti-NMDAR encephalitis include sudden behavioral, memory, and personality changes that progress to seizures, autonomic instability, and coma.
However, high-grade DCIS showed more copy number changes than low/intermediate-grade DCIS with specifically involved genes, supporting a model in which different histological grades of DCIS are associated with distinct genomic changes that progress to IDC in different routes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com