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For any two genotypes on a genotype network, there exists a sequence of small genetic changes that leads from one genotype to the other, without ever changing the native phenotype.
Traumatic brain injury (TBI) initiates a complex cascade of neurochemical and signaling changes that leads to neuronal apoptosis, which contributes to poor outcomes for patients with TBI.
This myocardial lipotoxicity results in alterations in the inflammatory cytokines levels and evokes a cascade of disparaging changes that leads to cardiac damage.
A number of studies have suggested that change in protein expression that starts the cascade of changes that leads to a diseased tissue need not always be gross or dramatic.
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"And it's a build-up of this which likely causes changes that lead to cancer".
Madrick traces the regulatory and cultural changes that led to the current woes.
Her stand against animal testing challenged the whole cosmetics industry to make changes that led to the European ban.
Ms. Stone said she thought the changes that led to federal approval of Wyoming's wolf plan were mostly cosmetic.
Changes that lead to complexity are more obvious than those that lead to simplicity, since they create something that was not there before.
Anna Wiener: I agree with you, Adrian: there's nothing morally superior about making product changes that lead to short-term revenue dips.
Throughout the extended period of time that it takes for cells to acquire the abnormal changes that lead to cancer, they transmit encoded information to their daughter cells.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com