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Such changes suggest substantial alterations, if not complete loss of the cobalt corrin ring coordination.
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While the significant CSPs of the minor species compared to wt Ub and major phosphoUb species suggest substantial changes, the secondary structure prediction showed only small changes (Fig 2E).
Although the findings of such analyses should be regarded mainly as hypothesis generating, statistical significance may suggest substantial changes in the diagnostic performance of the test under study as the covariate changes.
Sometimes counselors will use their knowledge of the admissions process to suggest substantial changes in a student's career.
The review group's 46 recommendations, spread over 304 pages, suggest substantial changes to the way the NSA, the FBI and the CIA do business.
The age group–specific incidence rate proportion profile graphs for 8 HIV and malaria scenarios suggest substantial changes in iNTS incidence rates as the HIV prevalence and proportion of population at risk for malaria increase.
Therefore, inconsistency of frequencies of the two haplogroups in the ancient samples with the patterns revealed from contemporary data may suggest substantial changes in haplogroup frequencies over the last 40,000 years from the predominance of haplogroup 2 to the predominance of haplogroup 1. Parallel haplogroup replacement has been reported for North American grey wolves.
These data, along with the determined changes suggest that TCA produce substantial systemic organ toxicity in rats during the period of a 52-day subchronic exposure.
On Friday, House Republicans presented Senate Democrats with a nine-page document suggesting substantial changes in the bill.
Attendance at multiple tutoring sessions increased by nearly the same amount, suggesting substantial changes in study habits in response to a simple and inexpensive intervention.
This suggested substantial changes in the J3 region and prompted us to sequence the entire genome of one ACME-positive and one ACME-negative t024 isolate.
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