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The slightly decreasing basal area of B. africana over the last 40 years cannot be explained by climate change as its current range extends to areas with conditions similar to climate changes predictions (Curtis and Mannheimer 2005; De Cauwer et al. 2014).
To assess the degree of differential prediction exclusively attributable to sequence annotation changes, predictions from newly added or deleted miRNA records were not considered, and only predictions from records common to both releases but having a sequence change were included in the analysis.
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This table shows the difference between real changes and changes prediction for the proposed approach and the proposed approach applied to model described in [40].
Also, this paper presents the bed changes prediction at seawalls toe using artificial neural networks on the basis of experimental data to widen the range of application.
The most commonly used evaluation of sequence-based stability changes prediction methods is on unseen mutations.
Therefore, stability changes prediction methods should be evaluated only on mutations in previously unseen non-homologous proteins.
A similar procedure, unseen-residue cross-validation, was used for the evaluation of a three-state stability changes prediction method [ 21].
Commonly, stability changes prediction methods are evaluated using a cross-validation where different mutations of the same protein can be randomly distributed across different folds.
Because of this correlation in the available data, stability changes prediction methods should be evaluated solely on mutations in previously unseen non-homologous proteins.
Commonly, stability changes prediction performance is evaluated using cross-validation which randomly divides all data set examples into k folds where k−1 folds are used for training and one fold for testing.
It has been shown previously that stability changes prediction can be guided by observing structural properties describing the secondary structure and accessible surface area of the mutated residue [ 25].
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