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We have focused on the conspicuous changes of translation efficiency of members of the trans-sialidases family.
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Accordingly in the bacterial genome-level, it implies that the change of translation initiation mechanisms (meanwhile with the change of using translation apparatus), which happens between the genes deriving from a common ancestor, is linearly dependent on the phylogenetic relationship in these species.
Analyzed in closely related bacterial genomes, our results imply that the change of translation initiation mechanisms, which happens between the genes deriving from a common ancestor, is linearly dependent on the phylogenetic relationship.
The genetic code is an enduring feature of biology: only rare circumstances result in changes to translation of the code, at least in nature.
Moreover, fold-change values of translation states (Δlog2 TL) of the whole genome (n = 22,746) were plotted onto Arabidopsis biochemical pathways and analyzed for functional bias of gene expression using MapMan v3.5.1R2 [ 62].
Changes in rates of translation or mRNA and enzyme degradation may significantly modify the quantity of enzymes available from a given amount of transcript.
Observational findings indicate both intervention groups experienced positive, significant changes in improved workstation arrangements and computing postures, with the WP+T intervention group exhibiting a higher, significant change of behavioral translation.
As for more complicated gene structure variations that cause change of protein translation, such as gene fusion, alternative splicing, it is even more difficult to identify and validate from proteomics level.
These changes might reflect temperature-dependent changes in the rate of translation of these proteins, in the activity of phosphatases, and/or changes in the activity of STPKs that use these proteins as the substrates.
This method explores the ability of mRNAs to change their rate of translation initiation with temperature.
Essentially, the authors suggest that mildly deleterious synonymous substitutions in protein-coding genes related to neurodevelopmental functions change the efficiency of translation process.
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