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Pathologic changes of the receptor site (cysts, tumors, osteomyelitis, etc).
Patients were ineligible if one of the following criteria was matched: Irradiation of the implant area Pathologic changes of the receptor site (cysts, tumors, osteomyelitis, etc).
This ligand-receptor complex formation also imposes conformational changes of the receptor which will result in an activation of the transfer of phosphate groups.
transmission of the stimulus by inducing conformational changes of the receptor iii.
Here we describe another case that involves partial conformational changes of the receptor upon binding of the peptide.
This can be rationalized as a steric effect in M100 position: when mutated into valine or alanine (smaller in size), wider conformational changes of the receptor are allowed.
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Maximum responses in the BRET assay must also be interpreted carefully since this response is very sensitive to conformational changes of the receptor-Luc molecule, which could be introduced by the truncation and mutation.
Opposite consequences of the signaling by SRI and SRII in response to photostimuli have been attributed to opposite conformational changes of the receptors based primarily on the direction of their SB proton movements and confirmed by electron paramagnetic resonance spectroscopy.
We studied protein expression of both receptors ex vivo by intracellular staining, thereby avoiding alterations caused by steric impairment, internalization and conformational changes of the receptors induced by ligands or Aabs.
Because the efficacy of HAIgG-induced ROS was not altered, the disparities must lie in the conformational changes of the receptors during cross-linking, which results from antigen binding.
In summary, the work by Dang et al. provides a new model for receptor-mediated entry of picornaviruses into host cells that depends on the pH-triggered conformational change of the receptor molecule.
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