Sentence examples for changes of the dna from inspiring English sources

In order to probe the DNA-helicate interactions responsible for the DNA binding and remarkable changes of the DNA secondary structure induced by a tetracationic bi-metallo helicate [Fe2(L1)3]4+ (L1 = C25H20N4), we have designed and synthesised derivatives with hydrophobic methyl groups at different positions on the ligand backbone.

primers were used for investigating the significant changes of the DNA isolated from liver tissues.

At higher voltages, the channel shows a main low-conductance state probably caused by electric-field-induced changes of the DNA pore in its conformation or orientation.

The binding could also induce conformational changes of the DNA, increasing the accessibility of the DNA for nucleases and leading to hypersensitive sites.

To account for changes of the DNA methylation, we applied the basic model of DNA methylation introduced by Sontag et al. (2006) which describes the parallel action of maintenance and de novo DNA methyltransferases (Smith & Meissner, 2013).

The in vitro interaction of desmin and DNA is preferentially targeted to exposed single-stranded sites of repetitive and mobile DNA sequence motifs and seems to induce changes of the DNA configuration [ 181].

H2O2 and other ROS are known to cause conformational changes of the DNA-binding domain of certain TFs [ 72- 74].

These validation experiments did not result in any significant changes of the DNA-protein formation except for PPARα.

The observations and insight of RolR structures reveal a unique inducer-regulator recognition and binding mode and special structural change of the DNA binding domain.

However, the conformational change of the DNA upon protein binding is significantly higher when multiple proteins bind to it than is observed when single proteins bind.

A mutation, conversely, is a permanent change of the DNA sequence following an exposure or event.