Sentence examples for changes of tau from inspiring English sources

Circular dichroism (CD) studies did not demonstrate any secondary structural changes of tau protein after addition of Zn II) ions at pH 7.2.

Wells et al. applied multiparametric MRI, containing high-resolution structure MRI (sMRI), a novel chemical exchange saturation transfer (CEST) MRI, DTI, and ASL, and glucose CEST to measure changes of tau pathology in AD transgenic mouse [44].

There were no changes of tau protein expression in black bears.

However, previous studies on longitudinal changes of tau and Aβ42 in individual patients with AD and elderly controls report somewhat inconsistent results.

Conformational changes of tau result in its disassociation from the microtubule and self-association into aggregates.

Our data reveal that the changes of tau profiles and phosphate kinases in scrapie-infected hamsters are time-relative events.

In the neocortex of hibernating black bears we found a conformational change of tau protein.

A mock antibody, DC51 [ 39], which does not bind to tau, did not influence the conformational change of tau, resulting in unaltered thioflavin T fluorescence.

Sy et al. [ 39] found in AD transgenic mouse, the change of tau protein from soluble to insoluble was related to the inflammatory response because of the increase of the activity of GSK-3.

The phosphorylation sites AT180 and AT8 were detected by western blotting in pro- and anti-aggregant mice but not in control littermates and Tau knockout mice (Additional file 4: Figure S2b-c) and we found weak immunoreactivity against the MC1 epitope demonstrating conformational change of Tau in that region (Additional file 4: Figure S2d).

The insignificant changes of total Tau in the soluble fraction in vivo may be attributed to the low percentage of pTau in the total Tau pool.