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ROS are the main mediators of the age related intrinsic or external stress associated changes of stem cells.
Nemeth et al. suggested that modulation of Wnt signaling could affect the microenvironment, which led to the changes of stem cells.
73– 75 While some of the functional changes of stem cells arise intrinsically, others are imposed by age-related changes in the microenvironment or niche.
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This relationship was incorporated into functional mapping to characterize specific QTL that control the allometric change of stem biomass relative to whole-plant biomass.
Loosening was defined as an obvious change of stem position, progressive osteolysis, or progressive radiolucent lines.
This early subsidence and change of stem position may, however, cause some instability of the joint, resulting in dislocation.
The slightly quantitative alternation of each component concentration could result in change of stem cell state, self-renewal or differentiation.
Here it appears that they don't see a significant change of stem cell numbers in p53 mutants, but this is never clearly stated.
In our study, there was correlation between stem-neck angle and change in BMD in two superolateral (ROIs 2 and 3) and two larger zones (ROIs 7 and 9), which indicate that the change of stem-angle towards valgus may have some effect on loading of the femoral neck and, thus, on bone remodeling.
A stem-based total clade Teleostei is accepted herein and our results emphasize the arbitrariness of selecting a particular node to delimit Teleostei along the stem Teleocephala due to the potential changes of the stem group caused by addition of newly discovered as well as restudied taxa.
Consistent with the morphological change, expression of stem cell markers NANOG and POU5F1/OCT4 were reduced in BMP-2-treated H9 cells, and even more efficiently in BMP-2/6-treated H9 cells (Figure 2A, 2B).
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