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In order to further investigate quantitative changes of lipids in the recovery phase as compared to the sedentary controls, evaluation of statistical significance for all identified 115 lipid species were carried out across the groups (Table 3).
The availability of novel analytical and advanced instrumental as well as powerful informatics technologies has facilitated the characterization of global changes of lipids in metabolic conditions such as obesity [19], insulin resistance [20], atherosclerosis [21], diabetes [22], and hepatic steatosis [23] and has facilitated data integration in order to understand the biological system.
In order to investigate quantitative changes of lipids in the rimonabant intervention group as compared to the control, statistical significance for the mean difference of all identified lipids between the rimonabant group and the control group was tested using independent student t-test.
In this study, we used MD to assess the metabolic changes of lipids in mechanically ventilated patients with sepsis.
A BP term is considered as lipid related if that process involves modification, breakdown or other changes of lipids or lipid complexes.
The focus of the investigation was on adverse changes of lipids and glucose metabolism, which have been implicated in the pathogenesis of acute myocardial infarction and type-2 diabetes [ 19, 20].
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DSG could also attenuate the abnormal changes of lipid profiles, including TC, TG and LDL, in pregnant db/+ mice.
However, little is known about the changes of lipid classes and the mechanism underlying the enhanced lipid production as imposed by irradiance and nitrogen starvation.
Objective: To determine, by a simple fluorescence method, sperm plasma membrane alterations related with changes of lipid bilayer that, together with routine semen analysis, could help to elucidate the causes of the unexplained male infertility problems.
In apoptotic cells, there are changes of lipid composition of plasma membrane: phosphatidyl serine transfers from cytoplasmic part of bilayer to outer side, causing caspase cascade activation, chromatin condensation, and disorder of electron transport chain in mitochondria and eventually arresting ATP synthesis.
Thus, both spectroscopies demonstrated that dramatic changes of lipid composition occur during steatosis in addition to lipid accumulation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com