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Hu, J. et al. Gradual changes of gut microbiota in weaned miniature piglets.
Changes of gut microbiota and urine metabolites can thus be employed as new systems approaches for quantitative assessment and monitoring of health at the whole-body level with the advantage of measuring human health based on the results of interactions between the two genomes and the environment rather than just host genomic information.
To verify the relationship between CP and gut microbiota, a clinical experiment in mice was conducted to evaluate the variations of glutathione peroxidase (GSH-PX), total antioxidant capacity (TAOC), tumor necrosis factor alpha (TNF-α), transforming growth factor beta (TGF-β), lipase, trypsin and the overall changes of gut microbiota in feces.
Our results discovered significant changes of gut microbial components between gallstone patients and healthy subjects.
The taxonomic assignments and fold changes of gut bacterial components that were significantly changed (p < 0.05) are listed in Figure 1B.
However, its use has been associated with clinical recurrence of infection in up to 20% of cases, which has been attributed to antibiotic-induced changes of gut microbiota [ 29].
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Previous study showed the temporal change of gut architecture and function after weaned could be divided two periods: an acute change (about 5 days) occurs immediately after weaned and an adaptive and maturity phase13.
Arimatsu, K. et al. Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota.
The effects of dietary changes on gut metabolism were described and the potential influence of inter-individual microbiota differences was noted, in particular the presence/absence of keystone species involved in butyrate metabolism.
In summary, arsenic exposure induces a significant taxonomic perturbation in the gut microbiome, which in turn substantially alters the metabolomic profile of the gut microbiome, as evidenced by changes of diverse gut microflora related metabolites.
Elevated intake of BAs results in changes of the gut microbiota by means of inhibition of Actinobacteria and Bacteroidetes [22, 44].
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