Sentence examples for changes of disease from inspiring English sources
ELN 457946 was shown to resolve paralytic symptoms and to reverse histopathological changes of disease in animal models of multiple sclerosis (Dofiles, Elan Pharmaceuticals; unpublished data; 2006).
Figure 4 shows the comparisons of πS, πN and πN/πS between the early and late time points according to the changes of disease status (4 participants with consistent mild disease, 1 participant with conversion from mild to severe disease, 1 participant with consistent severe disease).
Therefore, biological and clinical significance of ∆mtDNA dynamics associating with changes of disease phenotypes remains to be answered.
The primary end point "changes of disease activity index" instead of remission rates is unusual for a larger study.
Two longitudinal studies failed to show ability of IFN-I activation to parallel acute changes of disease activity [ 6, 7].
Improvement or response, however, relates primarily to absolute or relative changes of disease activity, and actual activity at the endpoint will depend on the baseline values.
The patients were categorized as responders if a change of Disease Activity Score 28 = 1.2 was obtained at 3 months.
In our series, active smoking and L1 or non-L2 disease were associated with change of disease behaviour in patients with B1 phenotype at diagnosis.
A total of 13 patients had no change of disease at the previous chemotherapy: nine of them maintain SD, one had PR and three deemed in progression.
The probability of surgery in B1 patients without change of disease behaviour was minimal, a finding quite similar to that previously reported by others [ 11, 49].
