Sentence examples for changes of chromosomes from inspiring English sources

All uveal melanomas were analysed for the oncogenic GNAQ mutation and chromosomal changes of chromosomes 3 and 8.

There are, however, different observations on chromosomal positions [ 10- 15] as well as on positional changes of chromosomes during the cell cycle [ 16, 17].

With respect to the genomic regions commonly affected in hPSCs, the large-scale studies echoed the earlier individual reports showing non-random changes of chromosomes.

Based on nuclease-deactivated Cas9, termed dCas9, the CRISPR-Cas9 system can be used as an imaging tool to label genomic loci and visualize dynamic changes of chromosomes (Chen et al., 2013; Cheng et al., 2016; Fu et al., 2016; Ma et al., 2016; Qin et al., 2017; Wang et al., 2016).

We found a strong overlap between these abnormalities, especially as regards changes of chromosomes 5, 7 and 17.

A broader definition of CIN also includes segmental or structural changes of chromosomes (Geigl et al. 2008).

The changes of chromosome number and karyotype are suggested to be caused by Robertsonian translocation, e.g. the fission of metacentric chromosomes at the centromeric region to generate more telocentric chromosomes (Karasawa and Saito 1982; Jones 1998).

Changes of chromosome 17 copy number (aneusomy) are extremely frequent in breast cancer [ 10].

Most frequent are changes of chromosome 7, trisomy 8, and complex aberrant karyotype which is defined by three or more chromosomal aberrations [ 9, 22, 61].

To detect the changes of chromosome number in the cells, we used 'AlleleBalance (AB)' variant annotations provided by the GATK, which was calculated based on the read depth of a reference allele (REF) and an alternative allele (ALT).

Therefore, the possible effect of the epigenetic change of chromosomes 16p11.1 and 13.1 on cancer development should be verified in further researches.