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Cancer initiation and progression follow complex changes of cellular architecture and biomechanical property.
To date, a number of studies have been conducted to investigate compensatory changes of cellular gene expression of PAMs upon PRRSV infection.
A whole-cell modeling framework is presented in which an assumed reaction network determines both concentration changes of cellular components and cell geometry.
Previous studies have revealed that changes of cellular morphology may also lead to changes of cellular mechanical properties in some cases [10, 24].
The raise of intracellular calcium levels would result in various changes of cellular metabolism as well as the cell morphology.
Over expression of PSGAP in fibroblasts results in reorganization of cytoskeletal structures and changes of cellular morphology, which requires rhoGTPase-activating activity.
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Change of cellular morphology was observed using an inverted optical microscope (Zeiss Axiovert 200 M fluorescent microscope, Carl Zeiss Microscopy, Oberkochen, Germany) with a magnification of x40.
The early-phase effect of H2O2 on phase shift may be attributable to the change of intracellular permittivity by a change of cellular polarity.
The sensor unit with microfluidic system was designed to detect the concentration change of cellular acidic metabolites in the extracellular microenvironment rapidly.
Cartilage quality response was given as change of cellular response (including synthesis) by 27 of 33 studies, as change of signaling response by 21 of 33 studies, and as change of mechanical response by 9 of 33 studies.
Because the cell membrane is not only a barrier between the intracellular environment and extracellular world but also a regulator of many important biological processes such as signal transduction, material transportation, and energy exchange, we looked for variation in the cell membrane structure accompanying with the change of cellular function; in this case, the level of differentiation.
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