Sentence examples for changes of a broad from inspiring English sources

Upon exposure of molecular patterns of pathogens, TLRs initiate a cascade of intracellular signalling transduction that leads to secretion of inflammatory mediators, including cytokines and chemokines, inducing expression changes of a broad spectrum of genes that regulate defense function against pathogens.

Differential proteomic analysis of endothelial cells collected before or after cold-adaptation at 25°C demonstrated significant changes to a broad range of biological processes and a new phenotype of enhanced redox protection and down-regulated anabolic and energy-consuming processes.

The primary outcome measure was the change of a broad-scaled cumulative axial Unified Parkinson's Disease Rating Scale score (Scale II items 13 15, Scale III items 27 31) at '3-week follow-up'.

In her interview Thursday, Polgreen tied the rebranding and design changes to a broader reimagining of the site's mission in the wake of the presidential election. .

The impacts of systematic changes over a broad range of MCC temperature and of the carrier gas flow rate on the resulting retention time separately for representative analytes were investigated in this study.

Going forward, an improved understanding of the genes underlying parallel trait transitions will provide key insights into the repeatability of evolution, helping us to better predict the phenotypic effects of genotypic changes across a broad array of crops.

While most of the changes cover a broad range of criminal defendants and not solely those charged with capital crimes, many lawmakers were motivated largely by the intense negative attention focused on the state's death penalty during the presidential campaign of Gov. George W. Bush.

The optical properties of structured aluminum surfaces are of great interest in comparison to the properties of unstructured surfaces because the absorptance of structured aluminum changes over a broad range of visible wavelengths.

The changes are part of a broad reorganization aimed at bringing Fiat Auto, which reported a first-quarter loss of 429 million euros, or $404.7 million, back to profitability.

Hypoxia is a potent stimulus known to induce changes in expression of a broad array of genes.

The proposal is "revenue-neutral," meaning that even though the rate comes down, the amount of revenue collected will not change, because of a broader tax base.