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These changes likely occur over longer time periods, and the resulting feedbacks will be of group 2.3 in Fig. 2.
Although it remains difficult to determine which cells are responsible for these changes in the patient's fluids, these studies illustrates that bioenergetic changes likely occur in MS patients.
These conformational changes likely occur in TcUGM, based on the strong sequence identity of the active sites of eUGMs and the high structural similarity of the AfUGM-UDP and TcUGM-UDP complexes.
Therefore, we conclude that CD3+CD56+ NKT-like cells possess functional activity that counters the progress of HIV infection and that these changes likely occur as a protective mechanism to limit viral spread and help slow HIV progression to AIDS in HIV-infected individuals.
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Since currently there is no evidence indicating that 5-Aza-dC may have direct effect on histone modification, these histone modification changes likely occurred as a secondary event upon DNA demethylation and together facilitated the reactivation of epigenetic silenced genes.
In addition, substantial functional changes likely occurred through gains or losses of functional domains.
We suggest that such a conformational change likely occurs only after both substrates are simultaneously bound in the active site.
Such change likely occurred in our experiments at ≈ 30 wt% of smectite and ≈ 40 wt% of clay minerals.
These results support the hypothesis that resistance to VEGF pathway therapy is not solely the result of a permanent genetic change in the tumor or selection of resistant clones, but rather is due to a great extent to reversible changes that likely occur in the tumor and/or its microenvironment.
The distinctly asymmetric hexamer architecture of PCH-2 provides clues to conformational changes that likely occur during ATP binding, hydrolysis, and release.
NMR structures of the SLI cleavage site internal loop were determined that correspond to both the unshifted and shifted conformations and help explain the structural changes that likely occur at the cleavage site as a result of the helix shift.
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