Sentence examples for changes instrumental to from inspiring English sources

By identifying genes differentially expressed between preinvasive and invasive stages of lung cancer development (CIS and SCC, respectively), relative to both non-cancerous bronchial epithelium and precancerous metaplasia/dysplasia lesions (BE and PC, respectively), we propose to identify expression changes instrumental to both initiation (CIS) and progression (SCC) of lung cancer.

Those genes differentially expressed in CIS relative to the precancerous lesions/bronchial epithelium, and in invasive SCC relative to the precancerous lesions/bronchial epithelium, presumably reflect gene expression changes more instrumental to cancer initiation, and cancer cell invasion, respectively.

Equally, the obvious psychological resistance to change is detrimental when it stems from sloth or when fear of change is instrumental to the conservation of those entrenched power positions that innovators dare to challenge instead.

After Damaged, Ginn jettisoned many of the band's early classics and confounded punk purists with an ongoing series of lineup changes, instrumental and spoken-word tracks, and postpunk records that were each heavier, darker, and artier than the last.

Although they do not have any explanation yet as to why their skin goes through these changes, ongoing research could be instrumental to preparing astronauts for longer missions.

Bending of the central helix is instrumental to conformational changes occurring during target protein recognition.

Changes in the photosynthetic apparatus are instrumental to adjust energy conversion and growth and are also important for optimized resource allocation, e.g. in dependence on light and nitrogen availability [ 29].

Effects due to changes in instrumental design, e.g. read-out time, slit width and spectral sampling, have been taken into account.

Fig. 10 Gravity changes due to soil moisture, instrumental drift, regional/global water distributions and snow from 2009 to 2010.

The opening ceremony on 27 September 1871 was performed by Mayor Ashworth, who had been instrumental in the changes made to the building's design.

DORIS is shown to be much less sensitive to instrumental changes than GPS (only the switch from Alcatel to Starec antenna at Toulouse is detected as an offset of −4 mm in the ZTD time series).