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The control group had no significant changes in weight over time.
Changes in weight over time were analyzed by repeated measures.
Changes in weight over time among treatment completers are displayed in Table 2. Using an intent-to-treat approach produced similar results.
Differences between repeated self-reported values are an estimate of changes in weight over time, assuming reporting bias is constant within 1 year.
Adjustment for changes in weight over time, as proxy for changes in muscle mass with correlates well with serum creatinine values, did not change the results.
However, because the SF-36 was not originally designed to measure important QOL domains specific to obesity, a number of studies have found the SF-36, particularly the mental component summary, to be relatively insensitive to variations in body weight cross-sectionally or to changes in weight over time [ 2- 4].
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The association continues being statistically significant after having included the monthly sputum microscopy result as confounder [14], [15], [21], [22], pointing out that change in weight over time is an independent predictor of treatment outcome.
For patients from center 2 (Stockholm, Sweden) weight and self-reported change in weight over time were recorded.
Estimates of dry weight for females at day 9 post-emergence (and the related estimate of the change in weight over time) were based on uninjected females.
Change in weight over time is shown in Fig 2 B. ALT and AST increased during LY2605541 treatment and decreased slightly during GL treatment, resulting in a statistically significant treatment difference after 8 weeks of treatment (Table 2).
Generally, (24) t = 1, BW (t + 1 ) = BW (t ) − Δ BW, [ t = 1, 2, 3 … until BMI (t ) ≤ 13 ], where Δ BW is the change in weight over the time interval and this is defined from the relative utilisation of fat and protein (Eqn 22) in combination with the demand function for Ebee (Eqn 19), both of which depend on BW t).
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