Gibbons et al. (1994) discern a change in the significance of the helices and distinguish between modes I and II.
This way, it attempts to determine the maximum magnitude of the modifications made at the input of each step, regardless of the actual number of updates, that would still not produce any relevant change in the significance of the dataflow output results.
In this class, there is also a change in the significance of coefficients.
We also removed 62 related subjects and there was no change in the significance of the all covariates.
Secondary analyses additionally controlling for the Brief Symptom Inventory global measure of psychological and somatic distress yielded little change (< 1% reduction) in the parameter estimates and no change in the significance of the effects in any of the models.
Even after oral hypoglycaemic agent or insulin users were excluded from the patients with diabetes, the same analysis found no change in the significance of the results (data not shown).
When vitamin D, calcium and magnesium were entered together into a further model the association of total dairy and all dairy subtypes with type 2 diabetes became marginally more inverse, but there was no change in the significance of the associations (results not shown).
Even after adjusting the quartiles of low GI fruit intake according to change in BMI, the significance of the treatment difference previously observed in HbA1c remained unaltered.
Changes in the comparable housekeeping gene can lead to changes in the significance and expression of the target gene using RT-PCR approaches to quantifying gene expression [96], [97].
