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These tools lack however the sensitivity and specificity to detect small changes in the progression or regression of both early and late stages of fibrosis.
To assess the ability of the Motor Function Measure (MFM) to detect changes in the progression of spinal muscular atrophy (SMA).
The high frequency of mtDNA mutations among smokers also suggests a key role for early mitochondrial genetic changes in the progression of their tumors.
There were no remarkable changes in the progression of the severity of RBD that was also rare at baseline.
The other aspect is that obesity is also associated with changes in the progression of many cancers.
The mechanisms of renal fibrosis are associated with a series of dynamic pathological changes in the progression of renal injury.
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A change in the progression of the thermal phase behaviour of the OIPC in the presence of dendrimer is also shown, exhibiting the phase I (high temperature) structure at temperatures below the phase II-I transition.
A quantitative analysis of ossification in a number of rudiments revealed significantly less bone in the scapular blade, humerus, ulna and femur, but no significant change in the progression of ossification in the tibia in both muscleless mutants.
In the additive model, we assumed that the change in the progression and pain scores was increased two fold by possessing two copies of the specific allele, compared to having a single copy.
Retrospective clinical studies show conflicting results however: O'Brien et al. reported significant reductions in aortic valve calcification in AS treated with ACEi, while Rosenhek et al. found no change in the progression of aortic valve disease or calcification.
Breast lesions in dogs show cellular changes involved in the progression to invasive carcinoma.
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