"changes in the operation" is correct and usable in written English.
You could use it any time you need to refer to changes or modifications to the way that something works or operates. For example: "We have implemented some changes in the operation of the manufacturing plant in order to improve efficiency."
Beyond that, in the statewide primary election last week, chaos reigned in the most-populous counties, Broward and Miami-Dade, with last-minute changes in the operation of the new computerized touch-screen machines and insufficient training of poll workers.
Even more startling, Wright had persuaded the surgeons to accept changes in the operation itself; there was now, for instance, a limit as to which prostheses they could use.
On the day the trial was to begin, the company, Integrated Health Services, reached an agreement under which it will enter a three-year program requiring changes in the operation of its nursing homes.
Though their approaches differ, both call for changes in the operation of the patent office, agree that access to broadband must be expanded and advocate steps to encourage technically trained foreigners to enter and stay in the United States.
"We think Microsoft made significant positive changes in the operation system," a Kodak spokesman said yesterday.
The low-carbon society requires significant changes in the operation and planning of distribution systems.
An article on Wednesday about economic problems in Hungary misstated recent changes in the operations of Flextronics, an electronics company.
And he called for some changes in the operations of a federal scholarship program that places physicians in areas short of doctors.
The law authorizes federal prosecutors to go to court to force changes in the operations of local departments if it finds a "pattern and practice" of misconduct.
The Justice Department has conducted its inquiry since 1996, centering on excessive use of force by officers, under a 1994 federal law that authorized federal prosecutors to go to court to seek changes in the operations of local departments.
If the talks fail, prosecutors could seek authorization from the Justice Department to go to court under civil rights law and ask a judge to order broad changes in the operations of the Street Crime Unit and possible oversight by a federal monitor.
